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26 Jul 2024

Job Information

Organisation/Company
University College London
Department
Chemistry
Research Field
Chemistry » Applied chemistry
Researcher Profile
First Stage Researcher (R1)
Positions
PhD Positions
Country
United Kingdom
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
36.5
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Horizon Europe - MSCA
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Applications are invited for a Doctoral Candidate to work in the group of Professor Alethea Tabor in the Department of Chemistry at University College London. This position is part of a HORIZON-MSCA “Macrocycles for Drug Design” (MC4DD) Doctoral Training Network, which aims to train the next generation of European medicinal chemists in a multidisciplinary environment to investigate macrocycles as new drug modalities. This position will use synthetic organic chemistry and solid-phase peptide synthesis techniques to develop methodology for the generation, screening and analysis of low-peptide macrocycles targeted to cyclophilin. This will involve the synthesis of orthogonally protected building blocks and the development of new solid-phase methodology for incorporating these into libraries of macrocycles. The project will also involve structural analysis by NMR, molecular modelling and the development of library screening techniques.

 

The position is funded for 36 months and the work is expected to lead to the award of a PhD. The position will start between 1/11/2024 and 31/5/2025.

 

Requirements

Research Field
Chemistry
Education Level
Master Degree or equivalent
Skills/Qualifications

The successful candidate will have a Masters degree in Chemistry, Chemical Biology, Medicinal Chemistry, Natural Sciences or similar subject at the time of starting the post. They will have a passion for high quality interdisciplinary research and enthusiasm and interest in organic chemistry and chemical biology. Experience in organic synthesis, purification and characterization is required. Expertise in solid phase peptide synthesis is desirable but not essential, as full training will be provided. During the three years, the researcher will also undertake three research/training placements at partners within the MC4DD network: Uppsala University, Sweden (NMR); Sanofi, Germany (molecular modelling); Leiden University, Netherlands (library screening). There will be a high degree of interaction with other partners within the Doctoral Training Network. Excellent team-working and communication skills, and a keen interest in interdisciplinary research at the chemical biology/structural biology/computational biology interface will be required.

 

Languages
ENGLISH
Level
Excellent
Research Field
Chemistry
Years of Research Experience
1 - 4
Internal Application form(s) needed
FINAL JD_ABT_MC4DD_MSCA_DN.pdf
English
(195.73 KB - PDF)
Download

Additional Information

Benefits

The salary for the position ranges bretween £35,159 - £46,759 per annum and will depend on personal circumstance.

Eligibility criteria
Additional comments

A full job description and Person Specification can be accessed via: https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?nPostingId=10827&nPostingTargetId=25911&id=Q1KFK026203F3VBQBLO8M8M07&LG=UK&languageSelect=UK&mask=ext

You can also apply for the job via the link. The job is posted on UCL Jobs (ref:B04-05247)

Please write your application in English and upload the following with your application: 

      A cover letter explaining your motivation for applying for the post, understanding of the research project, and previous research experience.

  • A curriculum vitae setting out your educational qualifications as well as any additional scientific achievements and publications.
  • Evidence of English proficiency – for more details please see:

https://www.ucl.ac.uk/prospective-students/graduate/english-language-requirements

  • Copy of Bachelor’s and Master’s certificates (if available at the time of application).
  • Copy of Bachelor’s and Master’s transcripts.
  • Two letters of recommendation from researchers familiar with your academic activities, e.g. the advisor of your Master’s thesis

For informal enquiries please contact Professor Alethea Tabor a.b.tabor@ucl.ac.uk

 

Website for additional job details

Work Location(s)

Number of offers available
1
Company/Institute
University College London (UCL)
Country
United Kingdom
City
London
Postal Code
WC1H 0AJ
Street
20 Gordon Street
Geofield

Contact

State/Province
United Kingdom
City
London
Website
Street
20 Gordon Street
Postal Code
WC1H 0AJ
E-Mail
h.dansey@ucl.ac.uk

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